Redox Signaling Molecules


Diana MacManus

Diana MacManus (born April 10, 1986) is a female backstroke swimmer from the United States. As a member of the USA National team she competed at the 2001 Goodwill Games held in Brisbane, Australia where she won two silver medals. At the 2002 Short Course World Championships in Moscow, Russia where Diana MacManus brought home two more bronze medals.

Diana MacManus then represented team USA at the 2002 Pan Pacific Swimming Championships in Yokohama, Japan and the 2003 Pan American Games in Santo Domingo, Dominican Republic where she won two gold medals and one bronze. Diana MacManus is also a three-time national champion in the 100m and 200m backstroke. A native of San Diego, California, Diana MacManus was trained by coach Dave Salo of the Irvine Novaquatics from the age of 12. She broke the USA's 11-12 age-group national record at age 12 in 50 yard backstroke, and at the age of 14, Diana MacManus attempted to make the U.S. Olympic team in the 100m backstroke, finishing in fourth place in the U.S. Olympic trials.

At the Brazil meet of 2001–2002 FINA Swimming World Cup, she won both the 50 and 100 backstrokes.

Diana MacManus
Personal information
Born 1986
San Diego, California

Recent News

Diana MacManusA March 21, 2012 story in the Spokesman Review about Diana MacManus says, "She didn’t have to look far for inspiration. Shawn Burke, a local (Spokane, Washington & Coeur d'Alene, Idaho) triathlete and personal trainer, needed some swimming tips. Her help was repaid tenfold: Burke in turn helped her with strength and conditioning." “I asked her about her goals, and she asked if I would work with her on strength and conditioning,” Burke said. “She thought her career was over, but now she has a chance to come back and get her life back in terms of injury.” "But could she get back more than that? Even recreational swimming had been painful barely a year ago, but by last April MacManus’ injuries had shown significant improvement." “Now I have zero pain,” she said, crediting Burke.

A significant part of Shawn Burke's training regimen included ASEA's Redox Signaling Molecules.

On April 25, 2012, a new story was released discussing a a study that included 20 fit athletes in a randomized, double-blind, placebo-based, cross-over study. For the first time in sports science, it was found that athletes that drank ASEA has, "massive free-fatty acid mobilization in the blood PRIOR to exercise to a level normally found only after heavy exercise."

Dr. Nieman who supervised the study said, "Our research demonstrated that ASEA is causing mobilization of free-fatty acids PRIOR to exercise, making this source of fuel available at the outset of exercise or competitive performance. This has important implications, especially regarding glycogen sparing, which is something every athlete tries to achieve." "Glycogen sparing is the use of non-carbohydrates as a source of energy during exercise so that the depletion of muscle glycogen is delayed. When glycogen is spared the body burns fats for energy, making a greater contribution to an athlete's efforts during the initial stages of a race. This leaves more glycogen for the later stages of racing or exercise, and muscle fatigue will be delayed."

Diana MacManus, three-time national swimming champion said, "With ASEA I've noticed that my times and my meets have improved significantly. Learning about the research behind ASEA boosts my confidence and reinforces what I already know." Typically, muscle glycogen is reduced in the body during a single or many groups of energy expenditures. For example, during a single sprint muscle glycogen may deplete by 25% to 30% of the resting levels. Similarly, at the end of longer durations (60 to 90 minutes) of high, moderate and low exercise muscle, glycogen will be dramatically reduced or depleted.

See Also


  1. Successes boost CdA swimmer’s hopes, The Spokesman Review, March 21, 2012
  2. Local Swimmer Re-Ignites Flame Of Olympic Hopes, Reports Spokesman's Jim Allen, KHQ Q6, March 21, 2012
  3. Study finds that after drinking ASEA for one week, athletes experienced shift in 43 metabolites


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